Abbott Linezolid Infusion is an antibiotic formulation containing linezolid, an oxazolidinone antibiotic effective against a variety of gram-positive bacteria, including resistant strains. It is commonly used for treating serious infections in hospitalized patients.

Key Features:

• Indications:
  • Treatment of pneumonia (including ventilator-associated pneumonia)
  • Complicated skin and soft tissue infections
  • Infections caused by multi-drug resistant organisms, such as methicillin-resistant Staphylococcus aureus (MRSA)
• Dosage Form: Available as an intravenous (IV) infusion, typically in a bag or bottle containing 600 mg of linezolid for direct administration.
• Mechanism of Action: Linezolid works by inhibiting bacterial protein synthesis, specifically by binding to the 23S ribosomal RNA of the 50S subunit, preventing the formation of the functional 70S initiation complex.

Usage:

• Dosage: Follow the prescribed dosage from your healthcare provider. The usual dosage for adults is typically 600 mg administered every 12 hours, but it may vary based on the type and severity of the infection.
• Administration:
  • Administered via IV infusion over a specified period, usually 30 to 120 minutes, depending on the protocol established by the healthcare provider.
  • Ensure proper infusion techniques and monitor the patient for any adverse reactions.

Precautions:

• Allergies: Inform your healthcare provider of any history of allergies to linezolid or other antibiotics.
• Side Effects: Common side effects may include gastrointestinal issues (nausea, diarrhea), headache, and potential myelosuppression (decreased blood cell production). Serious side effects should be reported to a healthcare provider immediately.

Storage: Store at room temperature, away from moisture and direct sunlight. Follow specific guidelines for storage of the infusion solution.

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