HIV Prevention Education Hub
Understanding PrEP and HIV Prevention
Clear, judgement-free information on PrEP: what it is, how well it works, the different options, how it differs from PEP and how to get it in Nigeria.
What is PrEP?
PrEP stands for pre-exposure prophylaxis: HIV medicine taken by people who are HIV-negative, before any possible exposure, to stop the virus from taking hold. It is one of the most effective HIV prevention tools available, alongside condoms, regular testing and treatment for partners living with HIV.
~99%lower risk of HIV from sex when PrEP is taken as prescribed
74%+lower risk of HIV from injection drug use
2Mpeople are living with HIV in Nigeria
Sources: US Centers for Disease Control and Prevention, via NIH HIVinfo; UNAIDS 2024 estimates for Nigeria (adult prevalence 1.2%).
Types of PrEP
| Option | How it is taken | Good to know |
| Daily oral PrEP | One pill every day (usually tenofovir with emtricitabine or lamivudine) | The most widely available option. Works best when taken daily. |
| Cabotegravir injection | An injection every 2 months after starter doses | No daily pills. Availability is still limited. |
| Lenacapavir injection | An injection twice a year | Being rolled out in selected Nigerian states from 2026 through government programmes. |
Some people use "on-demand" oral PrEP around the time of sex, but it is only suitable for certain people. Ask a clinician which option is right for you.
PrEP vs PEP: what is the difference?
- PrEP is taken before possible exposure, on an ongoing basis, to prevent HIV.
- PEP (post-exposure prophylaxis) is an emergency 28-day course of HIV medicine started within 72 hours after a possible exposure, such as a broken condom, sexual assault or a needle-stick injury.
If you may have been exposed in the last 72 hours, don't wait. PEP works best the sooner it starts and will most likely not work after 72 hours. Get urgent, confidential PEP help on WhatsApp.
Starting PrEP: what to expect
- HIV test: a confirmed negative result is required before starting.
- Baseline checks: kidney function, hepatitis B and, usually, STI screening.
- Getting protected: how long it takes to reach full protection depends on the type of PrEP. Your clinician will advise you.
- Follow-up: an HIV test and check-in about every 3 months, plus regular refills.
HubPharm makes this simple: a confidential consultation, testing support, discreet delivery and refill reminders through Afiya, our AI health companion on WhatsApp.
PrEP in Nigeria
Oral PrEP is available in Nigeria through government-supported facilities and private providers. In 2026, the federal government, through the National Agency for the Control of AIDS (NACA), began rolling out the twice-yearly lenacapavir injection in selected states, with approval from NAFDAC.
If you'd like to start PrEP privately and without long queues, HubPharm can arrange a confidential consultation, connect you with testing and deliver your medicine discreetly in plain packaging.
PrEP myths and facts
- Myth: PrEP is only for certain groups. Fact: any HIV-negative adult who could be exposed to HIV can use PrEP.
- Myth: PrEP protects against all STIs. Fact: it only prevents HIV. Condoms help prevent other infections.
- Myth: PrEP has serious side effects. Fact: most people have none or mild ones that settle in the first weeks, and clinicians monitor you.
- Myth: you can start PrEP without testing. Fact: a negative HIV test is always needed first.
Related support
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Last updated: November 2026 · HubPharm Africa · For education only, not a substitute for medical advice.