Pyrox Combi is a combination medication that includes rabeprazole, amoxicillin, and clarithromycin. This formulation is used to treat Helicobacter pylori infections, which are associated with peptic ulcers. It works by reducing stomach acid and eradicating the bacteria.

Indications:
Pyrox Combi is indicated for:

• Eradication of Helicobacter pylori to reduce the risk of duodenal ulcers
• Treatment of peptic ulcers associated with H. pylori infection
• Management of gastroesophageal reflux disease (GERD) in conjunction with H. pylori treatment

Mechanism of Action:

• Rabeprazole: A proton pump inhibitor (PPI) that decreases gastric acid secretion, promoting healing of the stomach lining.
• Amoxicillin: A penicillin-type antibiotic that works by inhibiting bacterial cell wall synthesis, effectively killing the bacteria.
• Clarithromycin: A macrolide antibiotic that inhibits bacterial protein synthesis, further aiding in the eradication of H. pylori.

Dosage and Administration:

• Adults: The usual dosage is one tablet taken once daily, typically for a 10 to 14-day course, or as directed by a healthcare provider.
• It is recommended to take the tablet before meals for optimal effectiveness.

Side Effects:
Common side effects may include:

• Nausea
• Diarrhea
• Abdominal pain
• Headache

Serious side effects are rare but may include:

• Allergic reactions
• Clostridium difficile-associated diarrhea
• Liver function abnormalities

Storage:
Store at room temperature, away from moisture and heat. Keep out of reach of children.

Caution:
Consult a healthcare provider before use if you are pregnant, breastfeeding, or have a history of liver or kidney issues. Complete the full course of treatment as prescribed, even if symptoms improve.

Packaging:
Typically available in blister packs or bottles, containing 14 tablets or more.

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FAQ

What is Pyrox Combi used for? Pyrox Combi is used to treat stomach ulcers and duodenal ulcers caused by Helicobacter pylori (H. pylori) infection. It is also used to manage gastroesophageal reflux disease (GERD) where H. pylori is involved.

Where can I buy Pyrox Combi in Nigeria? From HubPharm Africa at hubpharmafrica.com. We are a PCN-licensed pharmacy based at 17 Osinowo Street, Ikosi Ketu, Lagos, with same-day delivery in Lagos and nationwide delivery across Nigeria.

How do I take Pyrox Combi? Take one dose in the morning and one dose in the evening, ideally 30 to 60 minutes before a meal. Each dose includes one Rabeprazole tablet, one Clarithromycin tablet and one or two Amoxicillin tablets as directed by your doctor. Swallow all tablets whole. Do not crush or chew them.

How long do I take it for? The usual course is 7 to 14 days. Always complete the full course even if you feel better after a few days. Stopping early allows the bacteria to survive and can cause antibiotic resistance.

Is Pyrox Combi a prescription medicine? Yes. Pyrox Combi is a prescription-only medicine (POM). You should only take it under the guidance of a doctor or pharmacist. Contact us on WhatsApp and our licensed pharmacists can guide you.

What are the possible side effects? Common side effects include nausea, diarrhea, headache, abdominal pain and a temporary change in taste, particularly a metallic or bitter taste from the Clarithromycin. If you experience severe skin rash, persistent vomiting or yellowing of the eyes or skin, stop taking it and contact a doctor immediately.

Who should not take Pyrox Combi? Do not take Pyrox Combi if you are allergic to penicillin, Amoxicillin, Clarithromycin, Erythromycin or Azithromycin. Use with caution if you have a history of heart rhythm problems or severe liver or kidney disease. Always tell your doctor about all medications you are currently taking before starting this treatment.

Can it affect my contraceptive pill? Yes. The antibiotics in Pyrox Combi may reduce the effectiveness of hormonal contraceptives such as the pill or patch. Use an additional barrier method such as condoms during your treatment course.

Is HubPharm Africa a licensed pharmacy? Yes. We are licensed by the Pharmacy Council of Nigeria, Licence No. LAG20247B39C9. All medicines we stock are genuine, verified and properly stored.

Do you deliver outside Lagos? Yes. We deliver nationwide. Lagos orders placed before 12pm get same-day delivery. Delivery time and cost for other states shows at checkout.

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Please note that price may increase due to exchange rate.

Ensure you check the updated price before making payment.