Description

Co-Mepiryl is a combination medication that includes gliclazide (2 mg) and metformin hydrochloride (500 mg). It is primarily used for the management of blood sugar levels in adults with type 2 diabetes mellitus, especially when diet and exercise alone are insufficient.

Product Overview:

Each Co-Mepiryl Tablet contains 2 mg of gliclazide and 500 mg of metformin, designed to provide a dual approach to glycemic control by stimulating insulin secretion and improving insulin sensitivity.

Key Features and Benefits of Co-Mepiryl:

• Dual Action:
  • Gliclazide: A sulfonylurea that stimulates insulin release from the pancreas, particularly effective for controlling postprandial (after meal) blood glucose levels.
  • Metformin: A biguanide that reduces hepatic glucose production and improves insulin sensitivity, helping to lower overall blood sugar levels.
• Effective Glycemic Control: The combination of these two medications enhances blood glucose management, providing more comprehensive control than either drug alone.
• Weight Management: Co-Mepiryl is generally associated with weight neutrality or modest weight loss, making it suitable for individuals with type 2 diabetes who are overweight.
• Convenient Dosing: The combination tablet simplifies the treatment regimen, making it easier to adhere to prescribed therapy.

Directions for Use of Co-Mepiryl:

• Dosage: The usual starting dose may vary based on individual needs, typically prescribed as one tablet taken once or twice daily, preferably with meals. Your healthcare provider will determine the appropriate dosage for you.
• Administration: Swallow the tablet whole with a glass of water. Do not crush or chew the tablet to maintain its effectiveness.
• Consistency: For optimal results, take Co-Mepiryl at the same time(s) each day.

Precautions and Side Effects of Co-Mepiryl:

• Common Side Effects: Potential side effects may include gastrointestinal symptoms such as nausea, diarrhea, and abdominal discomfort. These effects are usually mild and may improve with continued use.
• Serious Side Effects: Rare but serious side effects can include lactic acidosis (a serious condition associated with metformin) and severe hypoglycemia (low blood sugar) due to gliclazide. Seek immediate medical attention if you experience symptoms like unusual fatigue, muscle pain, or difficulty breathing.
• Monitoring: Regular monitoring of blood glucose levels and kidney function is essential during treatment.
• Drug Interactions: Inform your healthcare provider about all medications and supplements you are taking, as Co-Mepiryl may interact with other drugs.
• Medical Conditions: Discuss your complete medical history with your healthcare provider, especially if you have kidney or liver issues, or a history of pancreatitis.

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