Description

Janumet is a prescription medication that combines two active ingredients: sitagliptin and metformin. It is specifically designed to help manage blood sugar levels in adults with type 2 diabetes mellitus, especially when diet and exercise alone are not sufficient.

Product Overview:

Each Janumet Tablet contains 50 mg of sitagliptin and 1000 mg of metformin. This dual-action formulation works synergistically to improve glycemic control through different mechanisms.

Key Features and Benefits:

• Dual Action:
  • Sitagliptin: A DPP-4 inhibitor that increases incretin levels, enhancing insulin secretion and decreasing glucagon levels in response to meals.
  • Metformin: A biguanide that reduces hepatic glucose production and improves insulin sensitivity.
• Effective Glycemic Control: The combination of sitagliptin and metformin allows for more effective management of blood glucose levels, helping to maintain stable glycemic control throughout the day.
• Weight Neutral: Janumet is generally associated with a lower risk of weight gain compared to some other diabetes medications, making it suitable for overweight patients.
• Convenient Dosing: Typically taken twice daily with meals, this medication can help reduce gastrointestinal side effects associated with metformin.

Directions for Use:

• Dosage: The usual starting dose is one tablet taken twice daily. Your healthcare provider may adjust the dosage based on your individual blood glucose levels and tolerance.
• Administration: Swallow the tablet whole with a glass of water, ideally during meals to enhance absorption and minimize gastrointestinal discomfort.
• Consistency: For optimal results, take Janumet at the same times each day.

Precautions and Side Effects:

• Common Side Effects: Potential side effects may include gastrointestinal symptoms such as nausea, diarrhea, abdominal discomfort, and flatulence. These effects are often mild and can improve over time.
• Serious Side Effects: Rare but serious side effects include lactic acidosis (a rare but serious metabolic complication associated with metformin), pancreatitis, and severe allergic reactions. Seek immediate medical attention if you experience symptoms like unusual tiredness, muscle pain, or severe abdominal pain.
• Monitoring: Regular monitoring of blood glucose levels and kidney function is essential during treatment to ensure safety and effectiveness.
• Drug Interactions: Inform your healthcare provider about all medications and supplements you are taking, as Janumet may interact with other drugs.
• Medical Conditions: Discuss your complete medical history with your healthcare provider, especially if you have a history of kidney disease, liver issues, or pancreatitis.

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