Vastarel MR 35mg is a modified-release formulation of Trimetazidine, a medication used to manage stable angina pectoris (chest pain due to reduced blood flow to the heart). This innovative formulation allows for sustained release of the active ingredient, providing prolonged therapeutic effects throughout the day.

Indications:

• Treatment of stable angina pectoris in adults.
• Adjunctive therapy in patients whose angina is not adequately controlled by other medications.

Dosage: The typical dosage is one tablet of Vastarel MR 35mg taken twice daily, preferably with meals. Dosing may be adjusted based on individual patient response and physician guidance.

Mechanism of Action: Trimetazidine works by optimizing the energy metabolism of heart cells, allowing them to use glucose more efficiently under conditions of low oxygen supply. This helps to stabilize cardiac function, reduce ischemia (insufficient blood flow), and improve exercise tolerance in patients with angina.

Benefits:

• Provides effective relief from angina symptoms.
• Helps improve quality of life for patients with coronary artery disease.
• Modified-release formulation ensures consistent drug levels over an extended period.

Side Effects: Common side effects may include dizziness, headache, gastrointestinal disturbances, and fatigue. Rare but serious side effects can include movement disorders and allergic reactions. Patients should discuss any concerning symptoms with their healthcare provider.

Precautions:

• Use with caution in patients with Parkinson’s disease or other movement disorders.
• Not recommended for use in individuals with severe renal impairment.
• Regular monitoring may be necessary to assess effectiveness and tolerability.

Storage: Store at room temperature, away from moisture and heat. Keep out of reach of children.

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