Buy Bupropion 150mg Online in Nigeria – Antidepressant and Smoking Cessation Therapy

Buy Bupropion 150mg online from HubPharm Africa, a PCN licensed specialty pharmacy. Bupropion hydrochloride is a noradrenaline and dopamine reuptake inhibitor supplied as a prolonged release tablet. Depending on the licensed product, it is indicated for the treatment of major depressive episodes and as an aid to smoking cessation in adults who are nicotine dependent.

Bupropion occupies an unusual position among antidepressants. It has little effect on serotonin, which means it rarely causes the sexual dysfunction, sedation and weight gain associated with serotonergic agents. Instead it tends to be activating, which makes it useful where fatigue, low motivation and anhedonia dominate the clinical picture, and it is the antidepressant most often selected where sexual side effects have caused earlier treatments to fail.

For smoking cessation, treatment begins while the patient is still smoking, with a target quit date set in the second week. The most important safety consideration with bupropion at any dose is a dose-dependent risk of seizure, which is why the medicine must never be exceeded, never be crushed or split, and never be used in patients with a seizure history or an eating disorder. Every HubPharm order is reviewed by a pharmacist before dispatch. Same-day delivery within Lagos, 48 hours nationwide.

Key Features

• Distinct Mechanism: Bupropion acts on noradrenaline and dopamine rather than serotonin, which gives it a side effect profile unlike that of SSRIs and SNRIs.
• Low Rate of Sexual Dysfunction: Frequently chosen when sexual side effects have made a previous antidepressant intolerable, and sometimes added alongside an SSRI for the same reason.
• Weight Neutral to Weight Reducing: Unlike many antidepressants, bupropion is not typically associated with weight gain and is often associated with modest weight loss.
• Dual Licensed Role: Used both as an antidepressant and, in its smoking cessation presentation, as a pharmacological aid to quitting in nicotine dependent adults.
• Pharmacist Seizure-Risk Screening: Every order is screened against the contraindications that matter most with bupropion, including seizure history, eating disorders and abrupt alcohol or benzodiazepine withdrawal.

Frequently Asked Questions

What is bupropion 150mg used for?

Depending on the licensed product, bupropion 150mg prolonged release is used for the treatment of major depressive episodes and as an aid to smoking cessation in nicotine dependent adults, alongside motivational support.

How does bupropion work?

It inhibits the reuptake of noradrenaline and dopamine and acts as a nicotinic acetylcholine receptor antagonist. Raising dopamine and noradrenaline improves drive, energy and mood, while nicotinic antagonism blunts the reinforcing effect of nicotine and reduces craving.

How is bupropion dosed for smoking cessation?

Treatment usually starts at 150mg once daily for six days while the patient is still smoking, increasing to 150mg twice daily from day seven with at least eight hours between doses. The quit date is set in the second week and treatment typically continues for seven to nine weeks.

How is bupropion dosed for depression?

Treatment commonly starts at 150mg once daily in the morning and may be increased to 300mg daily if the response after four weeks is inadequate. The exact regimen depends on the specific product and is set by your prescriber.

Can bupropion tablets be crushed or split?

No. The prolonged release tablet must be swallowed whole. Crushing, chewing or splitting releases the entire dose at once and materially raises the risk of seizure.

Who should not take bupropion?

It is contraindicated in anyone with a current or past seizure disorder, a current or previous diagnosis of bulimia or anorexia nervosa, a known central nervous system tumour, severe hepatic cirrhosis, or bipolar disorder in an acute manic phase. It must not be taken during abrupt withdrawal from alcohol or benzodiazepines, or with a monoamine oxidase inhibitor or within 14 days of stopping one.

What is the seizure risk with bupropion?

The risk is dose dependent and is estimated at approximately 1 in 1000 at the recommended doses. It rises sharply if the maximum daily dose is exceeded, if tablets are crushed, or if other seizure threshold lowering factors are present. Bupropion should be stopped permanently and not restarted if a seizure occurs.

What are the common side effects?

Insomnia, dry mouth, headache, nausea, constipation, dizziness, tremor, agitation and sweating. Insomnia is common early in treatment and is often reduced by avoiding a dose close to bedtime while keeping the eight-hour interval between doses.

Does bupropion cause weight gain?

It usually does not. Bupropion is generally weight neutral and modest weight loss is common, which is one reason it is favoured in patients for whom antidepressant-related weight gain has been a problem.

Can bupropion be combined with other antidepressants?

It is sometimes added to an SSRI or SNRI by a specialist to address residual fatigue or sexual side effects. This must be prescriber-directed, as bupropion inhibits CYP2D6 and can raise the levels of several other psychiatric medicines.

Does bupropion carry a mood or behaviour warning?

Yes. Antidepressants, including bupropion, carry a warning about suicidal thinking and behaviour, particularly in patients under 25 and during the first weeks of treatment or after dose changes. Neuropsychiatric symptoms have also been reported during smoking cessation treatment. Report significant mood or behaviour change promptly.

Do I need a prescription to buy bupropion in Nigeria?

Yes. Bupropion is a prescription only medicine dispensed against a valid prescription from a physician registered in Nigeria.