QUETIAPINE 100MG TABLETS
₦20,000.00
Buy Quetiapine 100mg Online in Nigeria – Titration and Maintenance Strength Atypical Antipsychotic
Buy Quetiapine 100mg online from HubPharm Africa, a PCN licensed specialty pharmacy. Quetiapine fumarate is a second generation antipsychotic indicated for schizophrenia, for manic and depressive episodes in bipolar disorder, and for the prevention of recurrence in bipolar disorder.
The 100mg tablet is the workhorse strength of the quetiapine range. Standard titration in schizophrenia moves through 50mg on day one, 100mg on day two, 200mg on day three and 300mg on day four, so the 100mg tablet is the unit that makes controlled dose building possible. It is also widely used to fine-tune maintenance regimens and to step doses down during planned reductions.
Because quetiapine’s pharmacology changes with dose, 100mg sits in a different clinical territory from higher strengths. At this level the sedative antihistaminergic effect is prominent while dopamine D2 occupancy remains well below the antipsychotic range. HubPharm pharmacists confirm the indication and intended dose with every order and counsel on sedation, blood pressure and metabolic monitoring. Same-day delivery within Lagos, 48 hours nationwide.
Key Features
- Essential Titration Unit: The 100mg tablet supports the standard four-day escalation schedule used when starting quetiapine in schizophrenia and bipolar mania.
- Flexible Dose Adjustment: Allows precise upward and downward adjustment across the full therapeutic range without changing product.
- Supports Controlled Withdrawal: Gradual reduction is required when stopping quetiapine, and the 100mg strength makes a stepwise taper practical.
- Low Extrapyramidal Burden: Quetiapine has a comparatively low rate of movement side effects, a key reason it is selected for patients sensitive to those effects.
- Pharmacist Monitoring Support: Our team prompts for weight, blood pressure, fasting glucose, HbA1c and lipid review at each refill.
Frequently Asked Questions
What is quetiapine 100mg used for?
It is used in the treatment of schizophrenia, in manic and depressive episodes of bipolar disorder, and in the prevention of recurrence in bipolar disorder. It is most often used as part of a titration schedule or a maintenance regimen rather than as a standalone therapeutic dose.
Why is quetiapine started at low doses and increased?
Rapid escalation causes marked sedation and orthostatic hypotension. The standard schedule of 50mg, 100mg, 200mg and 300mg over the first four days allows the body to adapt while moving efficiently toward a therapeutic dose.
Is 100mg a treatment dose for schizophrenia?
Generally no. Effective antipsychotic doses in schizophrenia usually fall between 300mg and 750mg daily. At 100mg, dopamine D2 occupancy is well below the threshold associated with antipsychotic effect, and the dominant action is sedative.
Why has my doctor prescribed a low dose of quetiapine?
Low dose quetiapine is sometimes used for its sedative and anxiolytic properties rather than for antipsychotic effect. This use is common in practice but is outside the licensed indications in most jurisdictions, and the metabolic and cardiac risks still apply. It is a reasonable question to raise with your prescriber.
When should quetiapine 100mg be taken?
Immediate release quetiapine is usually taken twice daily. Where a single dose is prescribed, the evening is preferred because of sedation. Follow the schedule on your prescription.
What are the common side effects?
Drowsiness, dizziness, dry mouth, headache, constipation, increased appetite, weight gain and orthostatic hypotension. Sedation is often most noticeable at lower doses because the antihistaminergic effect is proportionally greater.
Will the drowsiness wear off?
Sedation frequently lessens over the first one to two weeks as tolerance to the antihistaminergic effect develops. If it remains disabling, tell your prescriber rather than stopping the medicine.
Can quetiapine 100mg be stopped suddenly?
No. Abrupt discontinuation can cause insomnia, nausea, headache, anxiety and irritability, and may precipitate relapse. Reduce gradually under medical supervision.
Does quetiapine interact with other medicines?
Yes. Quetiapine is metabolised by CYP3A4. Strong inhibitors such as ketoconazole and clarithromycin substantially raise its levels, while inducers such as carbamazepine, phenytoin and rifampicin reduce them. Alcohol and other sedatives compound drowsiness.
What monitoring is needed?
Weight and waist circumference, blood pressure, fasting glucose or HbA1c, and lipid profile at baseline and at regular intervals. Full blood count should be checked if signs of infection appear, and an ECG may be indicated in patients with cardiac risk factors.
Can quetiapine be used in pregnancy?
Data are limited and the decision must be individualised with your specialist, weighing the risk of untreated illness against medicine exposure. Neonatal withdrawal and extrapyramidal symptoms have been reported after third trimester exposure. Do not stop the medicine on your own if you become pregnant.
Do I need a prescription to buy quetiapine 100mg in Nigeria?
Yes. It is a prescription only medicine dispensed against a valid prescription from a physician registered in Nigeria.
Description
Quetiapine 100mg – Product Information
Active ingredient: Quetiapine fumarate 100mg, a second generation (atypical) antipsychotic of the dibenzothiazepine class.
Presentation: 100mg film coated tablets for oral use. Immediate release and prolonged release presentations exist and are not interchangeable dose for dose.
Indications: Schizophrenia. Manic and depressive episodes in bipolar disorder. Prevention of recurrence in bipolar disorder.
Legal category: Prescription only medicine.
How Quetiapine 100mg Works
Quetiapine antagonises dopamine D2, serotonin 5-HT2A, histamine H1 and alpha-1 adrenergic receptors, and its active metabolite norquetiapine additionally inhibits the noradrenaline transporter and acts as a partial agonist at 5-HT1A. The clinical expression of this profile depends heavily on dose. At 100mg, histamine H1 blockade dominates and produces marked sedation, alpha-1 blockade contributes to postural hypotension, while striatal D2 occupancy remains low, which is why antipsychotic effect is limited at this strength. As the dose rises through 300mg and above, D2 occupancy enters the therapeutic range and antipsychotic effect emerges. Quetiapine is metabolised principally by CYP3A4, with a plasma half-life of approximately 7 hours for the parent compound.




