Zoladex 10.8mg (Goserelin Acetate) Implant – 12-Weekly Hormone Therapy for Advanced Prostate Cancer

Zoladex 10.8mg is a goserelin acetate implant given under the skin of the abdomen once every 12 weeks. Goserelin is a gonadotrophin-releasing hormone (GnRH) agonist used in the hormonal management of locally advanced and metastatic prostate cancer, and alongside radiotherapy in selected patients.

Prostate cancer growth is driven by testosterone. Goserelin works by continuously stimulating, and then shutting down, the pituitary receptors that signal the testes to produce testosterone. Within a few weeks testosterone falls to levels comparable to surgical castration, without surgery, and it recovers if treatment is stopped.

The 10.8mg implant is the three-monthly presentation. The 3.6mg implant is the four-weekly version and covers a wider set of indications. Zoladex is administered by a healthcare professional, not self-injected. HubPharm dispenses it against a valid prescription with oncology pharmacist verification, and can coordinate with your urologist or oncology centre on scheduling.

Key Features

• One Implant Every 12 Weeks: Four administrations a year instead of thirteen, which matters for patients travelling long distances to a treatment centre.
• Medical Castration Without Surgery: Achieves testosterone suppression comparable to orchidectomy, and is reversible on stopping.
• Pre-Filled Single-Use Applicator: Supplied ready for administration by a trained healthcare professional.
• No Refrigeration Required: Stored below 25°C, which simplifies delivery to centres outside Lagos.
• Oncology Coordination: Our pharmacists track your 12-week cycle and prompt refills so a dose is not missed.

FAQ

What is Zoladex 10.8mg used for?

The 10.8mg implant is used in the hormonal treatment of locally advanced and metastatic prostate cancer, and together with radiotherapy in selected patients as directed by the specialist.

What is the active ingredient in Zoladex?

Goserelin acetate, a synthetic analogue of gonadotrophin-releasing hormone.

How often is Zoladex 10.8mg given?

Once every 12 weeks, administered by a healthcare professional as a subcutaneous implant into the anterior abdominal wall below the navel. Keeping to the schedule matters, so book the next appointment when you receive each implant.

What is the difference between Zoladex 3.6mg and 10.8mg?

Both contain goserelin. The 3.6mg implant is given every 4 weeks and covers a broader range of indications. The 10.8mg implant is given every 12 weeks and is used in prostate cancer. The specialist decides which fits the treatment plan. They are not interchangeable on a dose-for-dose basis.

How much does Zoladex 10.8mg cost in Nigeria?

Current pricing is shown above and reflects our sourcing at the time of listing. Contact our oncology pharmacy team for current pricing, availability, and support with HMO claims, since hormone therapy is a long-running cost that many patients need help planning for.

Can I inject Zoladex myself at home?

No. Zoladex is an implant placed under the skin with a specific applicator and must be administered by a trained healthcare professional. HubPharm can help you arrange administration alongside supply.

What is tumour flare and why does it matter?

In the first weeks of treatment goserelin briefly increases testosterone before suppressing it. In some patients this can temporarily worsen symptoms such as bone pain or urinary difficulty. Specialists commonly prescribe an anti-androgen tablet starting before the first implant and continuing for several weeks to cover this period. Tell your team immediately if bone pain or urinary symptoms worsen after the first implant.

How long does it take to lower testosterone?

Testosterone typically falls to castrate levels within about three to four weeks of the first implant, and your specialist will confirm this with blood tests.

What are the common side effects?

Hot flushes and sweating are the most common. Reduced libido, erectile dysfunction, tiredness, mood changes, breast tenderness or enlargement, and injection site bruising or discomfort also occur. These reflect low testosterone and should be discussed with your team rather than endured silently.

Does long-term Zoladex affect the bones?

Prolonged testosterone suppression can reduce bone mineral density. Specialists often monitor bone health and may advise calcium, vitamin D, weight-bearing exercise or bone-protective treatment during long-term therapy.

What monitoring is required during treatment?

PSA and testosterone levels to confirm the treatment is working, plus periodic checks of bone density, blood glucose, lipids, blood pressure and weight during long-term use.

What happens if an implant is late?

Testosterone can begin to rise if the interval stretches well beyond 12 weeks, which may reduce the effectiveness of treatment. Contact your specialist and our pharmacy team as soon as you know a date will slip so supply can be arranged.

How is Zoladex stored?

Store below 25°C in the original packaging. Refrigeration is not required. Keep out of the sight and reach of children and do not use after the expiry date.

Can HubPharm deliver Zoladex outside Lagos?

Yes. Same-day delivery within Lagos, 48 hours nationwide, and international shipping. Because no cold chain is required, delivery to centres outside Lagos is straightforward. Speak to our team on WhatsApp at +234 705 050 5001.